Sepsis and Bacterial Infections

Bacteria are microscopic single-cell microorganisms (microbes) that are all around us. Most are harmless, and many are helpful. For example, bacteria in your intestines (gut) help break down the food you eat so your body can digest it. However, some types of bacteria can cause bacterial infections, which in turn can cause sepsis.

Sepsis, which was often called blood poisoning, is the body’s life-threatening response to infection. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Suggested Citation:
Sepsis Alliance. Sepsis and Bacterial Infections. 2025. https://www.sepsis.org/sepsisand/bacterial-infections/

Reviewed May 9, 2025.

 

More About Bacterial Infections

Examples

Bacteria must enter your body for them to cause an infection. So you can get a bacterial infection through an opening in your skin, such as a cut, a bug bite, or a surgical wound. Bacteria can also enter your body through your airway and cause infections like bacterial pneumonia. Other types of bacterial infections include urinary tract infections (including bladder and kidney infections) and dental abscesses, as well as infections caused by MRSA, Group B Streptococcus, and C. Difficile. Infections can also occur in open wounds, such as pressure ulcers (bed sores). Pressure ulcers are caused by constant pressure on the skin for extended periods or rubbing. For example, a senior who is bedridden could develop sores on the coccyx (tailbone) area, elbows, heels, or anywhere else where there is constant contact with a bed or adapted “easy chair.”

The name of one type of infection, septic arthritis, may be confusing to some people because it is not sepsis, despite its name. Septic arthritis is an infection in the joint fluid. However, this type of infection can also lead to sepsis. It can be caused by bacteria, as well as other microbes.

Sometimes bacterial infections are “secondary infections.” For example, if you contract COVID-19 – a virus – your body is in a weakened state and could also develop bacterial pneumonia. You would then be fighting both a viral infection and a bacterial one.

Symptoms

Bacterial infections present in many ways, depending on the part of the body affected. If you have bacterial pneumonia, you may experience

  • Fever
  • Cough, with phlegm
  • Shortness of breath
  • Sweating
  • Shaking chills
  • Headache
  • Muscle pain
  • Fatigue
  • Chest pain with breathing

If you have a urinary tract infection, you may have some of these symptoms:

  • Sudden and extreme urges to void (pass urine)
  • Frequent urges to void
  • Burning, irritation, or pain as you void
  • A feeling of not emptying your bladder completely
  • A feeling of pressure in your abdomen or lower back
  • Thick or cloudy urine – it may contain blood
  • Fever

The common element with most bacterial infections are:

  • Fever
  • Chills
  • Pain or discomfort in the affected area

But if the infection is in a joint, that joint and the surrounding area will likely hurt; if you have a sinus infection, you will probably have a headache and foul nasal discharge, and so on.

Prevention

Not all infections can be prevented, but the chances of spreading these infections can be greatly reduced by following these tips:

  • Wash your hands often, particularly if you are in a healthcare facility.
  • Keep wounds clean and covered.
  • Avoid sharing personal items, such as razors.
  • Eat a healthy diet. Malnutrition, not consuming enough nutrients for your needs, can lower your body’s ability to fight
Treatment

Most often, treatment for a bacterial infection is with antibiotics. They could be taken orally (by pill, liquid, or capsule), injection, drops, topical (cream or ointment), or intravenously (by IV). The treatment may be very short, or it could go as long as several weeks, depending on the type of infection and how it reacts to the antibiotics. Sometimes, the infection will not go away, and your doctor may have to try a different type of antibiotic.

Celebrities

Actress Ashley Park was treated for tonsillitis that progressed to sepsis. Other celebrities, like singer Chris Young and radio personality Casey Kasem, developed wound infections. Learn about more celebrities who had sepsis here.

 

Related Resources

Sepsis and Bacterial Infections – Chinese

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Sepsis and Bacterial Infections – Tagalog

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LA SEPSIS Y LAS INFECCIONES DENTALES

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LA SEPSIS Y LAS INFECCIONES BACTERIANAS

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Prevention

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Meningitis

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Dental Infections

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Cellulitis

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C. difficile

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Bacterial Infections

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Appendicitis

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Erin C.

Diagnosed with uterine carcinosarcoma August 2018, followed by radical hysterectomy. Was stage 1B very aggressive grade 3-4. Port surgically implanted and started chemo. Having completed 9 of 18 chemotherapy infusions, next I was on a 4 week break, before undergoing 30 rounds of radiation. (Sepsis and Cancer) My ninth infusion was the day before Thanksgiving 2018. Around the first week of December, I felt as if I had twisted my right ankle. That lasted a few days, then I was driving home from the grocery store and I turned my head to the right, to double check my lane change, ... Read Full Story

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Christine Krzeminski

In October 2022, I was a happily married mother of three young children, all under the age of 10. At the time, I was in good health and actively engaged in various family activities. Although I was feeling slightly unwell, I did not consider it a cause for concern. The next thing I remember is waking up 12 days later in the ICU, where I was informed of my diagnosis: sepsis caused by Haemophilus influenzae. I had developed unexpected abscesses on my legs and experienced significant cognitive impairment due to a brain infection. I later learned that my husband had ... Read Full Story

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Kassy Espinoza

Take care of your open wounds-clean them and bandage them because any bacteria can get into your body and it can cause sepsis. Exactly one year ago today I was diagnosed with sepsis and septic shock syndrome. I got bit by a spider but that’s not what caused the infection – the open wound is what caused me getting sepsis/septic shock syndrome. (Sepsis and Bacterial Infections) I remember going to the hospital because I was feeling very weak and I knew something was going on. The hospital sent me back home that morning. Later that night I couldn’t take anymore ... Read Full Story

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Gary Barrett

I was a healthy active 49 year old, participating in every sport I could find, after feeling unwell for about 10 days with pain and inflammation I went to the doctors I was told I had just pulled a muscle in my side and not to worry. At 1am I woke my wife up to say I could not stand the pain anymore and needed the hospital. She rushed me there and I collapsed at the entrance. I was unconscious for most of the following day, unaware of that I was losing the battle to live. The doctor, who I ... Read Full Story

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Rose Aumen

As a registered nurse, I knew when assessing patients in the Emergency Room the appearance/signs/symptoms of sepsis. I never thought I would become a sepsis patient myself. I was in pretty good health for a 65-year-old female. March of 2024 I had chills that morning, My right leg was hurting the day before and was still somewhat painful but tolerable. I took two Tylenol and went back to bed. After resting I felt pretty good, Later that evening I suddenly was unable to walk and had severe pain in my right hip. Bacteremia and sepsis took over my entire body. ... Read Full Story

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Other Topics

Bacterial Infections