Sepsis and Group A Streptococcus

Group A Streptococcus, also called group A strep, is a bacterium that can cause many different infections. These may cause sepsis.

Sepsis, which was often called blood poisoning, is a life-threatening emergency that happens when your body’s response to an infection damages vital organs and, often, causes death. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Suggested Citation:
Sepsis Alliance. Sepsis and Group A Streptococcus. 2026 https://www.sepsis.org/sepsisand/group-a-streptococcus/

Updated July 17, 2026.

 

More About Group A Streptococcus

Examples

Group A bacteria cause several types of infections, most commonly:

How group A strep spreads

Group A strep bacteria live in your nose and throat. They spread through droplets from coughing or sneezing, or by direct contact with the mucus. You might breathe droplets in if you’re close enough when an infected person coughs or sneezes. As well, the droplets may land on a solid object that you touch later. This type of contact may also occur if people who are infected blow their nose and touch an object before washing their hands. Either way, if the bacteria are transferred to your hand or fingers and you put your hand to your face, you can become infected.

If skin is infected, as with cellulitis or impetigo, the bacteria must come in contact with a spot of skin that had an open area, such as a cut, scrape, or bite. The opening may be so tiny that you didn’t notice anything beforehand. Impetigo is common among young children as they share toys and play together.

Invasive group A strep disease

While it’s common for group A strep to exist in your throat and nose, and on your skin, it is not common inside your body. When these bacteria enter your body, they can cause infections such as necrotizing fasciitis (often called “flesh eating disease”) and toxic shock syndrome. These are invasive group A strep infections.

Symptoms

Group A strep infection symptoms depend on where the infection is. The common symptoms include pain in the affected area, redness, and swelling. If the infection progresses or is a systemic infection, such as scarlet fever or toxic shock syndrome, you would develop fever, muscle aches, and flu-like symptoms.

Prevention

Preventing an infection from group A strep is the same as with other types of similar infections:

  • Wash your hands often and thoroughly.
  • Avoid people who are coughing, sneezing, or have other signs of a respiratory virus.
  • Clean open wounds with clean soap and water. You may want to use antibiotic ointment. Keep the wound protected (covered).
Treatment

Treatment for the infections include appropriate antibiotics. Sepsis caused by group A strep should be treated urgently with both antibiotics and IV fluids. For people with necrotizing fasciitis, surgery will remove the affected tissue.

Related Resources

Information Guide

Strep Throat

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Information Guide

Necrotizing Fasciitis

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In February 2025, while visiting family in Dallas, Texas, I suddenly developed what seemed like ordinary indigestion—an upset stomach that I thought would resolve with a good burp. I tried mints and TUMS, but neither helped. When someone suggested Alka-Seltzer, I drank one dose and then a second when the first brought no relief. That decision only worsened the situation, severely bloating my stomach and intensifying the pain. My cousin drove us the full 18 hours straight back home to Kannapolis, North Carolina, stopping only for gas and bathroom breaks. I rode in the back passenger seat while my husband ... Read Full Story

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Matthew H.

Matthew was a 9-year-old boy that went into severe septic shock from a Strep A bacterial infection in November of 2018. (Sepsis and Group A Streptococcus) He had typical flu-like symptoms that changed very quickly. Not only did he have a bacterial infection in his blood, it settled in his bones and joints, resulting in septic arthritis in his hip. After 10 days in the ICU, he was able to go home with a PICC line, a walker and close monitoring. Matthew remained some what healthy until February 2020 when he was, yet again, septic but this time was from ... Read Full Story

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Wayne G.

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Nicholas Mata

Nicholas was 11 years old when sepsis changed his life forever. He was a gifted young athlete, tall for his age (almost 6ft) and passionate about football. He dreamed of playing professionally one day and loved spending time with his teammates and friends. In December 2023, Nicholas was in 5th grade and living the life of a healthy, active boy, until a sudden illness turned into a fight for survival. On December 23, Nicholas developed a fever, dizziness, nausea, and weakness. At the emergency room, he had a heart rate of 130, low blood pressure, abnormal EKG, and dehydration. Despite ... Read Full Story

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Other Topics

Group A Streptococcus