Sepsis and Surgery

Surgery is a procedure that can affect your body in many ways aside from the actual reason for the operation.  Surgical procedures can be major, like open heart surgery, or minor, like a biopsy. What they have in common is an incision. Any type of surgical procedure exposes your body to infection and other complications, some of which could develop into sepsis.

Sepsis is a life-threatening emergency that happens when your body’s response to an infection damages vital organs and, often, causes death. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Suggested Citation:
Sepsis Alliance. Sepsis and Surgery. 2026. https://www.sepsis.org/sepsisand/surgery/

Updated July 17, 2026.

 

More About Surgery

Sepsis After Surgery

Infection after surgery can cause sepsis. This could be infection in the incision (the opening in the skin) or an infection that develops after the surgery, such as pneumonia or a UTI.

When you have surgery, it is important to monitor the incision, watching it for signs of infection. This would be:

  • Increasing redness around the incision
  • Pus or other fluid coming from the incision
  • Warmer than usual skin around the incision
  • Increased pain around the incision
  • Fever
  • Fatigue

Pneumonia is not uncommon after having surgery, which is why it is important to get up and about as quickly as is possible after the operation. Deep breathing and coughing exercises are also helpful in keeping your lungs clear. Patients who needed a ventilator to help them breathe are also at a higher risk of developing pneumonia.

Other infections, such as UTIs may develop if you had to be catheterized (a tube inserted into your bladder). The longer the catheter remains in place, the higher the risk of infection.

Celebrities

Singer Bobby Darin and actor Jamie-Lynn Sigler both developed sepsis after surgery. Learn about more celebrities who had sepsis here.

Related Resources

Information Guide

Surgery

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Hope Johnston

My journey began with a life-threatening complication following a routine tubal ligation. (Sepsis and Surgery) I presented to the ER with clear, alarming symptoms, but my reality was dismissed. Because I had undergone surgery only the day before, the medical team mistakenly attributed my escalating condition—including the free air and fluid in my abdomen—solely to that procedure. I was left to sit in the ER for 14 hours before anyone enacted a sepsis protocol. During those 14 hours, a bowel perforation was allowed to wreak havoc on my system, inevitably spiraling into full-blown septic shock. (Sepsis and Perforated Bowel) By ... Read Full Story

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Kelly Tripp

There are moments in life that change you forever. Moments that make you realize how quickly everything can shift and how important it is to listen when your body is trying to tell you something. After having surgery on May 13, I was home recovering and trying to take it easy. At first, I believed everything I was feeling was just part of the normal healing process. I was tired, uncomfortable, and focused on resting. But as the days went on, something did not feel right. (Sepsis and Surgery) I started experiencing chills, low-grade fevers, headaches, chest tightness, stomach pain, and ... Read Full Story

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Sally Lucia

I am proud to say that I survived severe sepsis in 2001. I am now a quadrilateral amputee. Post surgery infection sent me back to the hospital where I spent four months fighting for my life. (Sepsis and Surgery) I endured more than 30 surgeries, as the infection ran rampant through my body. The expectation of fatality was undeniable. Eventually, they upped my survival chances , but expected that I would be brain dead. Obviously I am not either of those things!!! My life as a quadrilateral amputee has been challenging, but at the same time rewarding in many ways. ... Read Full Story

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Jeffrey Conz

I had 2 back surgeries, then came septic shock. (Surgery and Sepsis) I went to bed on December 23rd. I have a wife and four children. After going to bed, I simply didn’t wake up. My wife explained that she couldn’t wake me in the morning and called an ambulance. The ambulance called for a chopper and I was airlifted to the hospital. I’m told that I had a temperature of 108 and I suffered four heart attacks during the transition. I woke up on the 11th day only to realize I couldn’t talk, read, or even ask what happened. ... Read Full Story

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Julia Lee Bloom

Forever 32. Julia Lee Bloom died on January 26, 2023, less than a week after a routine, outpatient surgery to remove the endometriosis that had caused her ongoing pain due to her diagnosed PCOS. Her autopsy report listed her death as a result of Streptococcus A, due to toxic shock syndrome. (Sepsis and Surgery, Sepsis and Group A Streptococcus, Sepsis and Toxic Shock Syndrome) She went to work on a Thursday as a hairstylist and greeted her clients with her beautiful smile and warm heart. She cooked supper that evening for her husband and her 2 young boys, ages 4 ... Read Full Story

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Surgery