Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition. It develops rapidly and drastically reduces the amount of oxygen your blood gets from your lungs.

Your lungs are filled with air sacs, which transfer oxygen from the air in your lungs to your blood. If you have ARDS, fluid leaks from the blood vessels in your airway into these tiny air sacs, limiting how much oxygen that can move from the air sacs to your blood. Other air sacs become unstable and collapse, also limiting their ability to function. Your body’s organs depend on the oxygen, and nutrients blood brings. If your blood does not have enough oxygen to meet your organs’ needs, they stop functioning properly. This may lead to the failure of other organs.

Although several causes can cause ARDS, including trauma or aspiration, the most common cause of ARDS is sepsis. Sometimes incorrectly called blood poisoning, sepsis is the body’s life-threatening response to infection. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Sepsis and septic shock can result from an infection anywhere in the body, such as pneumonia, influenza, or urinary tract infections. Worldwide, one-third of people who develop sepsis die. Many who do survive are left with life-changing effects, such as post-traumatic stress disorder (PTSD), chronic pain and fatigue, organ dysfunction (organs don’t work properly), and/or amputations.

Signs and symptoms of ARDS

ARDS symptoms are typical of someone who is having a hard time breathing. This includes:

  • Rapid breathing
  • Shortness of breath
  • Difficulty taking breaths
  • Low blood pressure
  • Organ failure
  • Confusion
  • Extreme fatigue

ARDS is a life-threatening condition and a medical emergency. If you are experiencing signs and symptoms of ARDS, call 9-1-1 immediately.

Treatment for ARDS

ARDS is a medical emergency. Before anything else, it is vital that you get more oxygen in your blood. A mask placed over your mouth and nose can supply you with oxygen, but you may need to be intubated if you are having too much trouble breathing. To do this, a doctor places a tube into your trachea (airway), usually through your mouth. This tube is then attached to a mechanical ventilator that will help you breathe by pushing air directly into your lungs.

Once the initial medical emergency is under control, the doctors then need to learn why you developed ARDS and treat the cause. If the cause was sepsis, this treatment would include antibiotics to treat the bacterial infection, intravenous fluids, and possibly medications called vasopressors to help raise your blood pressure. Intravenous fluids are important, but the doctors have to be careful not to give you too much. You need fluids to keep up your blood pressure, which allows your blood to flow through your blood vessels. Too much fluid could cause more fluid build-up in your lungs.


If you’ve had ARDS, you could be left with some lasting effects, such as scarring in the lung tissue and abnormal lung function.

Would you like to share your story about sepsis or read about others who have had sepsis? Please visit Faces of Sepsis, where you will find hundreds of stories from survivors and tributes to those who died from sepsis.

Suggested Citation: Sepsis Alliance. Sepsis and ARDS. 2022.


Reviewed February 9, 2022.

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Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition. It develops rapidly and drastically reduces the amount of oxygen your blood gets from your lungs.