Sepsis and Gallstones

Gallstones are hardened deposits that can form in your gallbladder, a small, pear-shaped organ found just below your liver on the right side of your abdomen. The gallbladder’s role is mainly to store bile, a digestive liquid your liver produces. Sometimes substances in the bile, particularly cholesterol, stick together to form stones. It is possible to have gallstones and not know it, but when a stone is big enough to become stuck or lodged, it can block the flow of bile.

Most people usually pass the stones without medical help. If the stones are stuck though, they can be quite painful, and they could cause inflammation and infection. Some people must have their gallbladder surgically removed. Either situation could potentially lead to sepsis. Sepsis, which was often called blood poisoning, is the body’s life-threatening response to infection. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Suggested Citation:
Sepsis Alliance. Sepsis and Gallstones. 2024 https://www.sepsis.org/sepsisand/gallstones/

Updated January 5, 2024.

 

More About Gallstones

Symptoms

It’s possible to have gallstones and not know it. However, if the stones are big enough and are causing irritation or they block the ducts, you could experience some of the following signs and symptoms. They often come on very suddenly, without warning:

  • Increasing pain in the upper right part of your abdomen
  • Intensifying pain just below your breastbone
  • Back pain between your shoulder blades
  • Pain in your right shoulder
  • Nausea and vomiting

If you experience any of these signs, please seek emergency help:

  • Abdominal pain so intense that you can’t sit still or find a comfortable position
  • Yellowing of your skin and the whites of your eyes
  • Tea-colored urine
  • High fever with chills
Risk Factors

Anyone can develop gallstones, but some people, such as those over 60 years, are at higher risk. Other risk factors include:

  • Sudden and quick weight loss
  • Obesity
  • Pregnancy
  • Eating a high-fat, high-cholesterol, or low-fiber diet
  • Family history of gallbladder disease
  • Diabetes
  • Taking some cholesterol-lowering medications or hormone therapy drugs with estrogen
  • American Indian or Mexican-American ancestry
Treatment

Treatment for gallstones depends on how much they affect you and if you are at risk for more stones and blockages. Gallbladder surgery removes your gallbladder, so you will no longer have stones. There are some medications that may dissolve some stones, but they are not commonly prescribed as they can take several months—even years—to work. They are not always effective.

Prevention

Not all gallstones can be prevented, but you can reduce your risk by following a healthy diet and losing weight in a healthy manner (not too drastically or quickly) if you are overweight.

Related Resources

Ashley D.

When I was only 13 I was diagnosed with gallstones and was told to follow up with a surgeon. When I went to the surgeon they ordered a CAT scan to make sure I did indeed have gallstones. The surgeon had told me I did not have gallstones and I went to go visit my family who at the time was living in Virginia. (Sepsis and Gallstones) When I got to Virginia things were fine at first but then I started to have stomach pain that would not go away for 2 days. I eventually went to the ER and ... Read Full Story

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Jerry Boisvert

It’s been an unhealthy rollercoaster ride to say the least over the last one-year. I have had more than my fair share of ailments ranging from Covid to nerve pain issues to recently severe sepsis that ultimately escalated to septic shock. It was Sunday, February 18, and we were driving home from Canada where we attended a funeral for the young son of my wife’s former manager. We had my wife’s current manager with us and after a long 8-hour drive, we brought our friend home and had dinner with he and his wife. We went home, unpacked, and put ... Read Full Story

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Elinor Goldie

First time 2007, bowel perforation, and two days lying in hospital as new year lack of staff. (Sepsis and Perforated Bowel) Scan two days later, hole in bowel.Emergency surgery and colostomy and woke up days later intensive care: sepsis and would be lucky to survive night. Family called. I did survive but kidneys and organs took bashing. Unwell, PTSD, I was terrified and still constipated. 2014 Ileostomy op and okay at first but off and on infections, dental and upper airways but no one mentioned sepsis. Pain ,nausea and more infections. They found gallstones but said they were fine. My ... Read Full Story

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Alyson C.

When you are pregnant you body goes through a lot of changes. You are tired, you feel ill, and you have aches and pains all over your body. So, that’s what I thought it was. One morning I was making breakfast for my family and the next thing I knew, I was laying in my husband’s arms and he was dialing 911. I remember seeing the black spots and sitting down; I don’t remember fainting. (Sepsis and Pregnancy & Childbirth) At the hospital, they said “this happens when you are pregnant. Fainting is common.” We went on with life, thinking ... Read Full Story

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Cynthia Andresen

In October 2019 I had a gallbladder attack at home and fainted, resulting in liver being involved along with the gallbladder. (Sepsis and Gallstones) I had sepsis that quickly went into sepsis shock and then PSS that included hallucinations, blindness (I am legally blind but this affected the eye that I have some vision in as well). (Sepsis and Hallucinations, Sepsis and Septic Shock) When I returned home I was not well and got worse; on Christmas my brother-in-law who is a nephrologist in OR called and did not like my voice. He flew out to TN the next day ... Read Full Story

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Gallstones