Perforated Bowel

A perforated bowel occurs when hole develops in your bowel wall, part of your gastrointestinal (GI) tract. The GI tract runs from your throat to your rectum. Food travels down your esophagus, into your stomach, where it empties into your small intestine, and then into your large intestine, or bowel. If the perforation occurs in your bowel, it may be called a perforated bowel.

If your GI tract is perforated, the contents may spill into your abdomen and cause peritonitis, an infection. Such an infection can lead to sepsis. Sepsis, which was often called blood poisoning, is the body’s life-threatening response to infection. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Sepsis and septic shock can result from an infection anywhere in the body, such as pneumonia, influenza, or urinary tract infections. Worldwide, one-third of people who develop sepsis die. Many who do survive are left with life-changing effects, such as post-traumatic stress disorder (PTSD), chronic pain and fatigue,  organ dysfunction (organs don’t work properly), and/or amputations.

How do you get a perforated bowel?

Your GI tract can perforate because of a GI-related condition or disease, or from a trauma. Conditions that may cause a perforation include:

  • Diverticulitis
  • Ulcerative colitis or Crohn’s disease
  • Toxic megacolon
  • Strangulated hernia, which can result in poor blood flow to the intestines
  • Injury from a medical procedure, such as a colonoscopy or surgery
  • Peptic ulcer disease
  • Forceful vomiting
  • Loss of blood or poor blood flow to the intestine caused by a blockage in the artery

The most common trauma that causes a perforated bowel occurs during abdominal surgery, when the surgeon may accidentally nick or cut the bowel and not notice it. Occasionally, a rupture or perforation may happen following bowel surgery, because the stitches or staples used to close the bowel come undone.

Other less common causes for a perforation include:

  • Knife or gunshot wound
  • Severe blow to the abdomen
  • Damage caused by swallowed foreign objects
  • Damage caused by swallowing a corrosive (caustic) substance
  • Appendicitis

Signs and symptoms of a perforated bowel

The signs and symptoms of a perforated GI tract come on gradually, getting worse, although they might not be too noticeable at first. They may include:

  • Severe stomach pain
  • Chills
  • Fever
  • Nausea
  • Vomiting

Diagnosis and treatment

A perforation anywhere in the GI tract is a medical emergency. The emergency room doctor will order x-rays and perhaps a computed tomography scan (CT scan). Blood tests look for signs of infection and blood loss from the perforation.

Surgery is usually performed to repair a GI perforation, particularly if it is in the bowel. Rarely, the doctor may prefer to take a wait-and-see approach, to see if the hole will repair itself. Meanwhile, the sepsis caused by the infection must be treated quickly with antibiotics and fluids.

In some cases, the surgeon must perform a colostomy or ileostomy. This surgery allows the contents of your intestines to empty into a bag, through a stoma, a hole created in your abdomen. The colostomy or ileostomy may be temporary, allowing the rest of your intestines to heal. You would then go for a second surgery so your surgeon can reattach your intestines, so you no longer need to eliminate your waste through the stoma. In other cases, the surgery is permanent.

In addition to surgery to repair the perforation, you will likely receive intravenous (IV) antibiotics to either prevent an infection from occurring or to treat one that has started.

Prognosis

A GI perforation is a medical emergency and requires quick recognition of the signs and symptoms, and rapid medical response. When this occurs, recovery should be complete.

If you suspect sepsis, call 9-1-1 or go to a hospital and tell your medical professional, “I AM CONCERNED ABOUT SEPSIS.” 

Would you like to share your story about sepsis or read about others who have had sepsis? Please visit Faces of Sepsis, where you will find hundreds of stories from survivors and tributes to those who died from sepsis.

Suggested Citation: Sepsis Alliance. Sepsis and Perforated Bowel. 2023. https://www.sepsis.org/sepsisand/perforated-bowel/

Updated Aug. 4, 2023.

Read Personal Stories of Sepsis and Perforated Bowel

Elinor Goldie

Survivor

First time 2007, bowel perforation, and two days lying in hospital as new year lack of staff. (Sepsis and Perforated Bowel) Scan two days later, hole in bowel.Emergency surgery and colostomy and woke up days later intensive care: sepsis and would be lucky to survive night. Family called. I did survive but kidneys and organs took bashing. Unwell, PTSD, I was terrified and still constipated. 2014 Ileostomy op and okay at first but off and on infections, dental and upper airways but no one mentioned sepsis. Pain ,nausea and more infections. They found gallstones but said they were fine. My ... Read Full Story

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Maria Headley

Survivor, Tribute

On November 3, 2020 Maria was taken to the ER with stomach pains. She was diagnosed with a twisted colon they did a arthroscopic surgery to untwist her colon. Then admitted her to the hospital. Then in 24 hours took her back in for surgery again this time they removed a small portion of her colon. She was doing fine in 24 hours she was taken back in for another surgery because of a swollen abdomen. They found another twist and a tear from the previous surgery. (Perforated Bowel, Sepsis and Surgery) Came out of surgery with a ventilator. They ... Read Full Story

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Juanita Marie Tafoya

Survivor, Tribute, Tribute

My sister Juanita Marie Tafoya, 39yr old female, passed away September 3, 2021 from sepsis. My sister was young and healthy. She went in for an ovarian cyst removal, my sister went and came home from the “cyst drain”not a cyst removal like they said. (Sepsis and Surgery) She started getting sick… fever, and bad pelvic pain. I remember my sister being bent over her bed because she said the pain felt better like that. She went back and they did exploratory abdominal surgery that see why my sis wasn’t recovering. They went back in a 2nd time and my ... Read Full Story

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Carly H.

Survivor, Tribute, Tribute, Survivor

It all started with a positive pregnancy test in Jan 2021. After multiple ER visits and working with an OB, they had finally determined that I had an ectopic pregnancy. I received a shot of methotrexate but that didn’t work for me as I was already 13 weeks along when they found the fetus in my Fallopian tube. I underwent a salpingectomy on March 18th, 2021 and my life changed forever. After being monitored in recovery, I was admitted for observation due to non stable and going in and out of consciousness. A CT would reveal that my bowel was ... Read Full Story

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Kimmie Young

Survivor, Tribute, Tribute, Survivor, Survivor

In April 2021, I got sick with diverticulitis, perforated colon and abscess the size of a golf ball on my colon. (Sepsis and Perforated Bowel) I spent multiple weeks in the hospital at various times in 2021. In July of 2021, I had my 1st surgery to remove the damaged colon tissue. When I awoke, I had a temporary loop ostomy on the right side of my abdomen. On November 1st, 2021, I went for a 2nd surgery to have the temporary loop ostomy reversed. There were some complications and I ended up with a left side ileostomy. The right ... Read Full Story

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Perforated Bowel

A perforated bowel occurs when hole develops in your bowel wall, part of your gastrointestinal (GI) tract. The GI tract runs from your throat to your rectum. Food travels down your esophagus, into your stomach, where it empties into your small intestine, and then into your large intestine, or bowel. If the perforation occurs in your bowel, it may be called a perforated bowel.