Sepsis and Blood Poisoning

Blood poisoning is a common term sometimes used to describe sepsis – it’s an old term used over generations. A doctor or nurse may say “blood poisoning” because this is a term many people are familiar with. But blood poisoning is not an accurate description of sepsis, and the two terms shouldn’t be used interchangeably.

Sepsis is not an infection in and of itself. Sepsis is the body’s life-threatening response to infection. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Sepsis and septic shock can result from an infection anywhere in the body, such as pneumoniainfluenza, or urinary tract infections. Worldwide, one-third of people who develop sepsis die. Many who survive are left with life-changing effects, such as post-traumatic stress disorder (PTSD), chronic pain and fatigue, organ dysfunction (organs don’t work properly), and/or amputations.

Suggested Citation:
Sepsis Alliance. Sepsis and Blood Poisoning. 2025. https://www.sepsis.org/sepsisand/blood-poisoning/

Reviewed May 9, 2025.

 

More About Sepsis

Impact

Scientists are working on discovering what exactly happens in sepsis. We know the inflammatory response causes problems such as internal blood clotting too much and too fast. This means that parts of the body don’t get adequate blood flow, and the body’s tissues don’t get the nutrients they need. The signs and symptoms of sepsis vary widely and can cause organs to fail, requiring life support.

While we still don’t know why our bodies react this way, we know that sepsis can cause:

  • Leakage from the lining blood vessel linings (much like a water hose with holes in it)
  • Low blood pressure (hypotension) with reduced blood flow to vital organs
  • Small clots throughout the body that prevent nutrients from reaching vital organs

These changes cause a person’s organs to stop working in many cases. Some of the signs include:

  • Heart – low blood pressure, fast pulse
  • Lungs – low oxygen level, problems breathing
  • Kidneys – making very little urine
  • Brain – confusion, coma

Related Resources

Information Guide

Blood Poisoning

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Susan H.

The Day I went missing. November 24, 2020 was the last day before Thanksgiving Break from high school. I am a 62 yr. old female, entering my 18th year of teaching special education. I had a history of diverticulosis, my father died when I was 18 of colon cancer. I was consistent with preventive colon care, but had been hospitalized for a night for diverticulitis in 2019. After the infection had cleared, a colonoscopy revealed severe diverticulosis, and gastro doctor advised 11 inches be taken out. My husband and I both met with him and got a second opinion, and ... Read Full Story

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Jessica Zachau

I was pregnant with my son when I went into septic shock. It began with severe back pain, a migraine, and extreme nausea. I went to the hospital and was told I was simply dehydrated. I was given fluids and sent home. However, the pain and symptoms continued, and something didn’t feel right. I decided to seek a second opinion at another hospital. After further testing and lab work, I was rushed to labor and delivery intensive care. I was diagnosed with septic shock. I remained hospitalized for over two weeks and experienced recurring episodes of sepsis caused by vesicoureteral ... Read Full Story

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Deborah Waller

My mother passed away on April 30th, 2024 after 48-hour battle in the hospital with sepsis. My mother started complaining of abdominal pain on April 27th in the afternoon after we went out to lunch. Shortly after we returned home from running errands and grabbing lunch at Kerby’s Coney Island, my mother started vomiting on and off until later in the evening. Initially, she thought, she may have gotten food poisoning. Shortly after midnight on April 28th, my mother passed out getting up to go to the bathroom. She was extremely pale and had no strength to get up. I ... Read Full Story

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Sean Simonic

The Night Everything Changed I was forty-four years old on May 5, 2018, when I loaded all four of my kids into the car to see Avengers: Infinity War. It was supposed to be a normal Saturday—a couple hours of popcorn, superheroes, and being a dad. But as the movie played, something inside me felt wrong. I kept coughing, over and over, each one hitting deeper than the last. Then, in the middle of that crowded theater, something exploded in my chest. It didn’t feel like a cough anymore—it felt like a bomb going off under my ribs. By that ... Read Full Story

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Gary Barrett

I was a healthy active 49 year old, participating in every sport I could find, after feeling unwell for about 10 days with pain and inflammation I went to the doctors I was told I had just pulled a muscle in my side and not to worry. At 1am I woke my wife up to say I could not stand the pain anymore and needed the hospital. She rushed me there and I collapsed at the entrance. I was unconscious for most of the following day, unaware of that I was losing the battle to live. The doctor, who I ... Read Full Story

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Blood Poisoning