Kidney Stones

People who have had kidney stones say there is nothing more painful. Kidney stones can develop in one or both kidneys. Some people get one kidney stone in their lifetime; others can get them more often.

Urine has no solids, but there are times when the crystals in urine join together to form a stone. Although several substances can form stones, the four most common are made of:

  • Calcium – common and can recur
  • Cystine – an amino acid
  • Struvite – develop as a result of urinary tract infections (UTIs)
  • Uric acid – a crystalline compound

Your kidneys are the beginning or top part of your urinary system. Urine is filtered in the kidneys and comes down through the ureters into your bladder, one from each kidney. The urine is held in the urinary bladder until it is emptied when the urine passes through the urethra and out the urethral opening.

A risk with kidney stones is a kidney infection, which can lead to sepsis. Sepsis, which was often called blood poisoning, is the body’s life-threatening response to infection. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Sepsis and septic shock can result from an infection anywhere in the body, such as pneumonia, influenza, or urinary tract infections. Worldwide, one-third of people who develop sepsis die. Many who do survive are left with life-changing effects, such as post-traumatic stress disorder (PTSD), chronic pain and fatigue, organ dysfunction (organs don’t work properly), and/or amputations.

How do you get kidney stones?

While we don’t know what causes stones to form, we do know that some stones form more easily than others. Dehydration and not consuming enough fluids can contribute to stone formation, as there may not be enough urine to wash out microscopic crystals.

Calcium stones, the most common kidney stones, seem to affect more men than women, and they are most often in the twenties when it happens.

Risks include:

  • Too much calcium in the urine caused by diseases, such as hyperparathyroidism
  • Having too much sodium, usually taken in through salt

Although food doesn’t cause stone formation, some people may be told to avoid high calcium foods if they are prone to developing stones.

Cystine stones are caused by a disorder that runs in families.

Struvite stones are virtually always caused by a urinary tract infection (UTI) due to an enzyme secreted by certain types of bacteria. Because people with shorter urethras have more UTIs, they also tend to develop more struvite stones. These stones can grow very large and block the kidney, ureter, or bladder.

Uric acid stones affect more men than women, and they can also occur in people who already get calcium stones. People who have high uric acid levels may have or develop gout.

What are the symptoms?

Some people don’t feel kidney stones until they move and try to exit the kidney. Some symptoms include:

  • Sharp, severe, cramping pain in the abdomen or side of the back
  • Pain can move to the groin or testicular area
  • Blood in the urine
  • Chills
  • Fever
  • Nausea
  • Vomiting

What treatments are available?

Because of the intense pain often caused by kidney stones, many people need pain relief. Many describe it as the worst pain they’ve ever felt.

If you have a kidney stone, you will be encouraged to drink a lot of water if you don’t have a medical condition that limits the amount you may have. The extra fluid is to help wash the stone through your urinary system.

If the stone doesn’t pass within a reasonable amount of time, your doctor may recommend extracorporeal shock wave lithotripsy (ESWL).  Shock waves are sent through to the stone to break them down into smaller pieces that can be passed. Sometimes, surgery may be needed.

The stone should be removed because of the high risk of infection, which could – in turn – lead to sepsis.

Can kidney stones be prevented?

While not all kidney stones can be prevented, there are ways to lower your risk of developing one or developing another one. The first and foremost way would be to drink enough fluids to ensure your urinary system gets flushed out well.

Your doctor could recommend avoiding certain types of foods, but that is an individual call. For certain types of stones, sometimes medications are prescribed to help reduce the risk.

If you suspect sepsis, call 9-1-1 or go to a hospital and tell your medical professional, “I AM CONCERNED ABOUT SEPSIS.” 

The information here is also available as a Sepsis Information Guide, which is a downloadable format for easier printing.

Would you like to share your story about sepsis or read about others who have had sepsis? Please visit Faces of Sepsis, where you will find hundreds of stories from survivors and tributes to those who died from sepsis.

Suggested Citation: Sepsis Alliance. Sepsis and Kidney Stones. 2023. https://www.sepsis.org/sepsisand/kidney-stones/

Updated February 7, 2023.

Read Personal Stories of Sepsis and Kidney Stones

Steve B.

Survivor

I had a procedure to remove a kidney stone. (Sepsis and Kidney Stones) Doctor said in and out same day operation. Well apparently my anatomy wasn’t very easy for her to navigate to find the stone and blast it out with her little laser tool. She then placed a tube in the ureter to prevent pain and damage when the stone passed. After the surgery I was still in pain that I never knew existed, so I was rolled down the hall to get a CAT scan. She got the results and brought her laptop to see what was going ... Read Full Story

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Sally Mayne

Survivor, Survivor

I am a sepsis survivor of 5 ½ years, and in 2018 I went into septic shock, had multi-organ failure, including lack of oxygen to my brain while medical staff rushed to save my life. This all began because of kidney stones that were blocking the opening from one of my kidneys and the infection soared through my body in an alarmingly short time. (Sepsis and Septic Shock, Sepsis and Kidney Stones) From the first symptom until the point I fell unconscious, it was a matter of 2-3 hours. At that point in my life, I had never heard of ... Read Full Story

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Madison Greathouse

Survivor, Survivor, Survivor

May 2023 I woke up from a nap with the worst abdominal pain I had ever experienced. After a few hours I went to the emergency room where I was diagnosed with a 6mm kidney stone at 20 years old, and was sent home with a referral to a urologist. (Sepsis and Kidney Stones) I had an appointment with my urologist on Monday and was scheduled for my procedure on Thursday to get the stone removed. The next few days I don’t remember much. I would wake up in the middle of the night with shaking screaming episodes that I ... Read Full Story

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Lora Kramer

Survivor, Survivor, Survivor, Survivor

The pain was unbearable it was worse then child birth. I had some pain in the morning but about mid afternoon it just hit so hard. I took pain reliefs but it turned into me vomiting with very high fever, I had the chills. The ambulance was called and when they took me to hospital I waited close on 8 hrs before the doc came. I remembered I had to give urine for tests but nothing after that, so apparently from what my partner told, me they rushed me to the hospital where the doctor told the paramedics and nurses ... Read Full Story

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Denise C.

Survivor, Survivor, Survivor, Survivor, Survivor

I was scheduled for kidney stone sugery (lithotripsy) for August 25, 2023. A urine sample before surgery indicated I had a UTI, and I was prescribed an antibiotic which I could take for 5 days before surgery (because I had been out of town when notified). (Sepsis and Kidney Stones, Sepsis and Urinary Tract Infections) I was assured by my urologist that 5 days of antibiotic was sufficient to treat the UTI. I did not think twice about this. After outpatient surgery, I was very tired (just wanted to sleep) and somewhat nauseous. My partner thought it was just a ... Read Full Story

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Kidney Stones

People who have had kidney stones say there is nothing more painful. Kidney stones can develop in one or both kidneys. Some people get one kidney stone in their lifetime, others can get them more often.