Perforated Bowel

A perforated bowel occurs when hole develops in your bowel wall, part of your gastrointestinal (GI) tract. The GI tract runs from your throat to your rectum. Food travels down your esophagus, into your stomach, where it empties into your small intestine, and then into your large intestine, or bowel. If the perforation occurs in your bowel, it may be called a perforated bowel.

If your GI tract is perforated, the contents may spill into your abdomen and cause peritonitis, an infection. Such an infection can lead to sepsis. Sepsis, which was often called blood poisoning, is a life-threatening emergency that happens when your body’s response to an infection damages vital organs and, often, causes death. Like strokes or heart attacks, sepsis is a medical emergency that requires rapid diagnosis and treatment.

Sepsis and septic shock can result from an infection anywhere in the body, such as pneumonia, influenza, or urinary tract infections. Worldwide, one-third of people who develop sepsis die. Many who do survive are left with life-changing effects, such as post-traumatic stress disorder (PTSD), chronic pain and fatigue,  organ dysfunction (organs don’t work properly), and/or amputations.

How do you get a perforated bowel?

Your GI tract can perforate because of a GI-related condition or disease, or from a trauma. Conditions that may cause a perforation include:

  • Diverticulitis
  • Ulcerative colitis or Crohn’s disease
  • Toxic megacolon
  • Strangulated hernia, which can result in poor blood flow to the intestines
  • Injury from a medical procedure, such as a colonoscopy or surgery
  • Peptic ulcer disease
  • Forceful vomiting
  • Loss of blood or poor blood flow to the intestine caused by a blockage in the artery

The most common trauma that causes a perforated bowel occurs during abdominal surgery, when the surgeon may accidentally nick or cut the bowel and not notice it. Occasionally, a rupture or perforation may happen following bowel surgery, because the stitches or staples used to close the bowel come undone.

Other less common causes for a perforation include:

  • Knife or gunshot wound
  • Severe blow to the abdomen
  • Damage caused by swallowed foreign objects
  • Damage caused by swallowing a corrosive (caustic) substance
  • Appendicitis

Signs and symptoms of a perforated bowel

The signs and symptoms of a perforated GI tract come on gradually, getting worse, although they might not be too noticeable at first. They may include:

  • Severe stomach pain
  • Chills
  • Fever
  • Nausea
  • Vomiting

Diagnosis and treatment

A perforation anywhere in the GI tract is a medical emergency. The emergency room doctor will order x-rays and perhaps a computed tomography scan (CT scan). Blood tests look for signs of infection and blood loss from the perforation.

Surgery is usually performed to repair a GI perforation, particularly if it is in the bowel. Rarely, the doctor may prefer to take a wait-and-see approach, to see if the hole will repair itself. Meanwhile, the sepsis caused by the infection must be treated quickly with antibiotics and fluids.

In some cases, the surgeon must perform a colostomy or ileostomy. This surgery allows the contents of your intestines to empty into a bag, through a stoma, a hole created in your abdomen. The colostomy or ileostomy may be temporary, allowing the rest of your intestines to heal. You would then go for a second surgery so your surgeon can reattach your intestines, so you no longer need to eliminate your waste through the stoma. In other cases, the surgery is permanent.

In addition to surgery to repair the perforation, you will likely receive intravenous (IV) antibiotics to either prevent an infection from occurring or to treat one that has started.

Prognosis

A GI perforation is a medical emergency and requires quick recognition of the signs and symptoms, and rapid medical response. When this occurs, recovery should be complete.

If you suspect sepsis, call 9-1-1 or go to a hospital and tell your medical professional, “I AM CONCERNED ABOUT SEPSIS.” 

Would you like to share your story about sepsis or read about others who have had sepsis? Please visit Faces of Sepsis, where you will find hundreds of stories from survivors and tributes to those who died from sepsis.

Suggested Citation: Sepsis Alliance. Sepsis and Perforated Bowel. 2023. https://www.sepsis.org/sepsisand/perforated-bowel/

Updated Aug. 4, 2023.

Read Personal Stories of Sepsis and Perforated Bowel

Shannon Martin

Survivor

On September 29, 2019 my day started out with me feeling a little nauseous so I thought I was coming down with something. Later in the day my stomach was cramping like it always does when I have to go number 2. Only I couldn’t go. Then the cramps turned to pain that continued to get worse. Finally I told my husband to take me to the hospital. By the time we got there the pain was so bad I couldn’t talk. I cried and vomited because that was all I could do. The rest was a blur. My husband ... Read Full Story

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Karl B.

Survivor, Tribute

In May 16th 2022, my mom took my father to the hospital as his neck had started bleeding and she could not get it to stop. As he was on blood thinners, she believed that they would stitch him up and they would be on their way home. When they got to the ER, it was discovered that my dad was in renal failure and had extremely low blood pressure. He was admitted to the hospital. His platelets were also very low and it was discovered that he had an infection in his neck. For a month he went back ... Read Full Story

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Michael Mark

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My father was diagnosed in October with having a weak heart. For the next 4 months he was admitted into the hospital every month for at least one week. The end of January, I walked into my father’s room finding him laying there but his face was blue. I called 911 and he was rushed to the hospital. He was initially diagnosed with pneumonia, then viral pneumonia, then sepsis. (Sepsis and Pneumonia) With a surprise, his heart function went from 40% back to 90%. He did recover from sepsis while in the hospital. The doctors stopped his IVs. He was ... Read Full Story

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Maria Headley

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On November 3, 2020 Maria was taken to the ER with stomach pains. She was diagnosed with a twisted colon they did a arthroscopic surgery to untwist her colon. Then admitted her to the hospital. Then in 24 hours took her back in for surgery again this time they removed a small portion of her colon. She was doing fine in 24 hours she was taken back in for another surgery because of a swollen abdomen. They found another twist and a tear from the previous surgery. (Perforated Bowel, Sepsis and Surgery) Came out of surgery with a ventilator. They ... Read Full Story

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Helen Decker

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August of 2021 I was diagnosed with diverticulitis. I followed doctor orders by taking antibiotics and a liquid diet. Pain worsened for a couple of months with scans only showing inflammation. I went to the hospital where I was put under observation for a three day period, receiving antibiotics through IV. Despite no improvement in symptoms, they discharged me since my white blood count went back into the normal range. 6 days later, I woke to rapid heart rate into the 160s and 180s, vomiting, shivering, a fever of 103.2, difficulty breathing and pain that made it difficult to walk. ... Read Full Story

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Perforated Bowel

A perforated bowel occurs when hole develops in your bowel wall, part of your gastrointestinal (GI) tract. The GI tract runs from your throat to your rectum. Food travels down your esophagus, into your stomach, where it empties into your small intestine, and then into your large intestine, or bowel. If the perforation occurs in your bowel, it may be called a perforated bowel.