In 2011, Sepsis Alliance recognized that more attention could be drawn to sepsis and sepsis awareness if there was a specific month dedicated to the cause. While efforts towards education for both the public and healthcare professionals are maintained throughout the year, having a dedicated Sepsis Awareness Month allows for organizations and facilities to organize activities for their staff, and for Sepsis Alliance supporters to make a concentrated effort on spreading information about sepsis.

The following year, the Global Sepsis Alliance, of which SA is a founding member, declared September 13th to be World Sepsis Day. This one day brings together people in health care and members of the public to recognize that sepsis is a global problem.